How to lose weight..Here's SECRET mantra

New York, Jan 13: You can blame your genes for your obesity as researchers have found 13 genes that carry variations associated with body mass index (BMI).

The researchers identified 14 genetic variations in 13 genes, including a risky copy variation -- a phenomenon in which sections of the genome are repeated -- that causes carriers to weigh 15 pounds more, on average, than individuals who do not carry the variation.

The gene is called MC4R and approximately 1 in 5,000 individuals carries this risk copy, which causes the gene not to produce any of the protein needed to inform the brain to stop eating.

"Our study has identified genes that play a crucial role in the neuronal control of body weight. They act in the brain in pathways that may affect people's food intake, hunger and satiety," said Ruth Loos, lead author of the study and professor at The Charles Bronfman Institute for Personalized Medicine at the Icahn School of Medicine at Mount Sinai.

"Individuals who inherit these genetic variations may find it harder to eat less or stop eating, as compared to those who did not inherit these variations."

For the study, published in the journal Nature Genetics, the researchers focused on a specific set of genetic variations that are likely to affect the function of genes and their proteins -- an approach that expedited the discovery of the causal genes that affect body weight.

It involved more than 250 research institutions. Genetic data from more than 700,000 individuals and 125 different studies were combined to form the largest genetic association study to date.

The researchers also identified two variants that may affect the function of a gene called GIPR.

By knowing the genes and the biological pathways through which they work, researchers believe they are a few steps closer to understanding why some people gain weight more easily than others, which is critical for developing effective treatments.


Related news

Don’t Miss

Baby Donald Trump is setting internet on fire..In PICS
Congress blows the bugle: Will go for coalition in 2019
HURRY: Now buy Samsung Galaxy S9, S9 Plus in just Rs 9900
Anti-Modi front..Raj Thackeray will tie up with Sharad Pawar?
Amit Shah defends Yogi despite Gorakhpur defeat
Corruption-hit Mauritius Prez resigns
Sad day..Kevin Pietersen says good bye to cricket
Delhi shamed..Senior citizen beaten to death in fight over water
Kangana does it again..don't miss
How Sindhu lost All England semis..The Inside Story
Congress vows to impose 5% cess on ultra rich if voted to power
Bypoll loss effect?Gorakhpur SSP,24 other top UP cops transferred
Shami fixed matches?BCCI anti-corruption staff meets pacer's wife
Mosquito bites bother Sonia at Plenary.. Covers herself with shawl,gets repellent gel
Rahul changes Twitter handle..From @OfficeofRG to @RahulGandhi
Before Emotional Hug.. Modi slogans are 'dramebaazi', says upbeat Sonia
To defeat Modi, Congress ready for 'Grand Alliance'
Jai Hind..Rajnath ready to enter Pakistan to protect Kashmir
Navratri 2018: First Day Mata Shailputri is worshipped
Bangladesh dressing room broken after Sri Lanka match
Sonia invokes Indira's Chikmagalur victory to inspire Congressmen
Country feeling tired under Modi, Congress will bring change: Rahul
This popular actress marries her Russian boyfriend
Did not get any call from Kapil to join new show, confirms Sunil Grover
Loveguru Karan Johar's SHOCKING prediction about Deepika, Ranveer
Desi Girl Priyanka visits this place after wrapping up Quantico
Congress Plenary Session: The warm hug says it all
Spy poisoning: Russia expels 23 British diplomats
24-hour power supply at 100 prominent temples during 'Navratri'
Congress ready to ally with 'all like-minded parties' to defeat BJP

Most Recent

Most Popular